藥物分類是屬於Aminoglycoside抗生素，機轉也是與16S核醣體RNA結合抑制蛋白質合成的起始和延伸步驟。
它對 E. histolytica(痢疾阿米巴)，D. fragilis(雙核阿米巴)和 G. lamblia(蘭氏賈第鞭毛蟲)以及Taenia saginata(無鉤絛蟲)，Taenia solium(豬肉絛蟲)，Diphyllobothrium latum(廣節裂頭縧蟲)，Dipylidium caninum(複孔絛蟲)和 Hymenolepis nana(短小包膜絛蟲)具有活性。
這種藥物很難被血液吸收，因此除非特別設計，並不能用於腸道外的感染。
由於它也可以抑制腸道細菌，所以在肝性腦病變也可以使用於抑制腸道細菌產氨
如何使用Paromomycin
用餐時口服這藥物，通常每天3次（每8小時一次）或按照醫生的指示服用。
治療劑量
阿米巴痢疾
肝性腦病變
Cryptosporidium parvum
絛蟲
在內臟利甚曼病(Visceral Leishmaniasis )也有治療的角色，劑量是11 mg / kg以IM的劑量給予治療VL，而cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL)也有部分效果
阿米巴痢疾
Oral dosage
Adults, Adolescents, and Children
25—35 mg/kg/day PO in 3 divided doses for 7—10 days.
肝性腦病變
Oral dosage
Adults
4 g/day PO in divided doses, at regular intervals for 5—10 days.
Cryptosporidium parvum
Oral dosage
Adults and Adolescents
500 mg PO 4 times daily for 14—21 days in combination with optimized antiretroviral therapy, symptomatic treatment, rehydration, and electrolyte replacement.
絛蟲
Oral dosage
Adults
1 g PO every 15 minutes for 4 doses.
Children
11 mg/kg PO every 15 minutes for 4 doses. Single dose regimens generally result in a lower cure rate and are not recommended, due to the low absorption of the antibiotic, and the inaccessibility of the cystoides that are buried within the intestinal villi.
在內臟利甚曼病(Visceral Leishmaniasis )也有治療的角色，劑量是11 mg / kg以IM的劑量給予治療VL，而cutaneous leishmaniasis (CL) and mucocutaneous leishmaniasis (MCL)也有部分效果
